Brains are not like computers. Our brains can quickly and easily spot familiar objects, like keys in a messy room, with very little effort. In contrast, even the best computers struggle to do this as fast or efficiently. This difference shows just how much more we need to learn about how our brains work to create smarter artificial intelligence.
To bridge the gap between neuroscience and Artificial Intelligence (AI), I seek to harness the efficiency of vision by understanding how neural computations govern sensory processes like vision and behavioral responses like eye movements.
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Laurent Perrinet is a computational neuroscientist (DR2 CNRS) at the Institut de Neurosciences de la Timone (UMR 7289, CNRS / Aix-Marseille Université), within the NeOpTo team. His research investigates predictive processing in the visual system — from single cortical cells to active vision and behavior — and its translation into neuromorphic algorithms. He has co-authored more than 63 peer-reviewed articles (h-index 30), supervised 6 completed PhD students and currently directs 3 PhD students (Alexandre Lainé, Matthis Dallain, Kevin Mairot). His work combines neurophysiology (Neuropixels recordings in marmoset), computational modeling (spiking neural networks, Free-Energy Principle) and open-source algorithmic development (MotionClouds, AnEMo, LogGabor).
Habilitation à diriger des recherches, 2017
Aix-Marseille Université
PhD. in Cognitive Science, 2003
Université P. Sabatier, Toulouse, France
M.S. in Engineering, 1998
SupAéro, Toulouse, France


From falcons spotting prey to humans recognizing faces, the ability to rapidly process visual information depends on a foveated retinal organization that provides high-acuity central vision while preserving low-resolution peripheral vision. This organization is conserved along early visual pathways, yet remains under-explored in machine learning. Here, we examine the impact of embedding a foveated retinotopic transformation as a preprocessing layer on convolutional neural networks (CNNs) for image classification. By applying a log-polar mapping to off-the-shelf models and retraining them, we achieve comparable accuracy while improving robustness to scale and rotation. We demonstrate that this architecture is highly sensitive to shifts in the fixation point and that this sensitivity provides an effective proxy for defining saliency maps that facilitate object localization. Our results demonstrate that foveated retinotopy encodes prior geometric knowledge, providing a solution for visual searches and a meaningful classification robustness and localization trade-off. These findings provides a proof of concept in order to connect principles of biological vision with artificial networks, suggesting new, robust and efficient approaches for computer vision systems.
We are recruiting a PhD student to work on neuromodulatory control of predictive processing in mouse vision, co-supervised by Ede Rancz (INMED) and myself.
This CENTURI project combines:
📄 Full project description 📬 Application form :rainbow_heart: We welcome applicants from all backgrounds and celebrate diversity and free creative thinking in our research environment.
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